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Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family.

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Usual adult dosage is 50 mg promethazine HCl with an appropriately reduced dose of narcotic or barbiturate and the required amount of a belladonna alkaloid.

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Promethazine is a prescription drug approved for various uses, including the treatment of nausea.

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